Angioedema (acute angioedema, angioedema, trofonevrotichesky edema, angioedema) - sharply growing rapidly passing allergic skin edema, subcutaneous tissue and mucous membranes, is a kind of reaction to exposure to a variety of biological and chemical factors.
Named after the German physician Heinrich Quincke first described it in 1882.Angioedema and susceptible adults and children, but often the disease occurs in women at a young age.In children and the elderly is rare.Manifestations of angioneurotic edema - an increase in the face or a part or limb.Skin color does not change.
are two types of angioedema: allergic and pseudoallergic.
Allergic angioedema, as well as other allergic diseases, is the result of a severe allergic reactions.Often combined with a food allergy, asthma, hives, hay fever.In other cases, the cause of angioedema is a drug allergy, food allergy, insect bites, worms and protozoa, blood diseases and autoimmune diseases.
cause allergic edema may be the impact of specific
Contributing factors to the occurrence of angioedema may be parasitic, and viral infections (giardiasis, hepatitis, worm infestation, etc.), diseases of the internal organs and the endocrine system (eg, thyroid).
occurs hereditary (pseudoallergic) angioedema.
Angioedema with similar allergic edema develops under the influence of substances that cause the formation of histamine - the same allergens.Swelling develops in the sensitized organism under the influence of specific allergens: flowers, animals, food, drugs, cosmetics, or nonspecific: stress, intoxication, infection, hypothermia.Contributing factors may include liver, thyroid (particularly for its reduced function), stomach, blood diseases, autoimmune diseases and parasitic.Often in this case, the disease acquires a chronic relapsing course.
In some cases the cause of angioedema can not be established (the so-called idiopathic edema).
Painless, fast growing, limited swelling of the skin, subcutaneous adipose tissue and / or mucous membranes, sometimes accompanied by a feeling of fullness of the skin.Most often angioedema is located on the lower lip, eyelids, tongue, cheeks, throat, and larynx and tongue edema can lead to suffocation - shortness of breath, cyanosis yazyka.Osobenno dangerous is angioedema of the larynx in the region.In this first noted hoarseness, "barking" cough, shortness of breath and then increases with shortness of breath.The complexion acquires a bluish tint, then abruptly bledneet.Krome of severe angioedema may be the beginning of even more severe immediate allergic reaction - anaphylactic shock.
possible local swelling of the lips, eyelids, scrotum, and oral mucous membranes (tongue, soft palate, tonsils), respiratory tract, gastrointestinal tract, urogenital area.Edema is rarely accompanied by pain, most patients complain of a feeling of tension fabrics.
appearance of angioedema in the intestinal mucosa can lead to abdominal pain, and in the lining of the bladder - a violation of urination.
The rare forms of angioedema include swelling of the meninges, the uterine lining, the synovium of joints.It appears characteristic numbness and itching.Easy angioedema quickly begins suddenly and quickly pass on their own.
Eliminates contact with the allergen;
prescriptions to improve the tone of the sympathetic nervous system (calcium supplements, ascorbic acid, ephedrine);
decrease in the parasympathetic activity (atropine) and histamine level:
antihistamines, including 2nd and 3rd generation - it
desloratadine (brand name: Eridez, Eden, Aerius, Loratek);
cetirizine (trade names: Tsetrin, Alerza, Allertek, Zetrinal, Zintset, Zyrtec, Zodak, Letizen S, Parlazin, Tsetirinaks, Allerkaps, Aleron);
Fexofenadine (trade names: Telfast, Feksofast, Feksadin).
needed vitamin - Ascorutinum prescribed to reduce vascular permeability;
Showing desensitizing therapy (ACTH, cortisone, prednisone) treatment B vitamins and gamma-globulin
hormone treatment in the absence of contraindications to hormone therapy is recommended in the hospital.
only reasonable prevention is to avoid contact with allergens, you must know your allergen and if the allergen has served drug, do not forget to report it on subsequent calls to the doctor.