Mechanism of allergy
Hippocrates, Avicenna, Galen described the cases of intolerance to certain foods, leading to gastrointestinal disorders and urticaria.Allergy haunts mankind since ancient times, but now has become much more allergens due to deteriorating environmental conditions and the dominance of home, food, and industrial chemistry.What is an allergy and why it occurs?
well known that the immune system protects human health from a wide variety of infections and other external influences.In the body, all protective proteins produced without exception - several kinds of immunoglobulins (A, F, G, E).IgE that participate in allergic reactions, usually not produced too much, for example they need to kill the worms.
But it turns out, absolutely all people respond to various external stimuli (house dust, household and industrial chemicals, animal dander, pollen and mold), a slight increase in the amount of IgE in the blood.
need for such increase is protective in nature: immunoglobulin E acts as guard dogs that catch on
How does this happen?When substances that trigger allergic reactions (allergens), enter the body, the immunoglobulins are thrown at them and "snap" together with allergens.Immunoglobulin E sit on the membrane so-called mast cells, inside which contain various active substances, including serotonin, acetylcholine, bradykinin, are responsible for the development of inflammatory symptoms.Histamine is ejected from the mast cells and allergy sufferers there is swelling of these places, there are itching, rash, discharge, such as from the nose.These reactions serve a protective biological function - dilates blood vessels, and are attracted to this place other active blood cells can also release substances that destroy foreign proteins.
immunoglobulins are specific when only respond to certain stimuli, such as pollen or any food product (eggs, chocolate).
In some diseases, such as hepatitis, AIDS, the number of immunoglobulins produced in the body can be reduced, so the allergic symptoms may subside.But at the same time a person is sharply reduced immunity to a variety of often very dangerous infections, and it is virtually defenseless against cancer.If you are a true allergies, you are lucky in the sense that it is unlikely that you are destined to be ill with another scourge of modern civilization - to get a malignant tumor.Your vigilant immune system simply does not allow it.According to US scientists from the National Cancer Institute, in various forms of allergy risk of brain tumors is reduced by 33 % - 51%.
So allergies - this increased reactivity of the immune system that occurs for various reasons and causes hypersensitivity to a variety of household, food, medicines and industrial irritants.They can be really dangerous and harmful to the health (eg medicines or household chemicals), and quite harmless, but the body still reacts to the invasion of foreign molecules inadequate.