Clinical tests of mucus from the nose

August 12, 2017 17:51 | Assays

In healthy people in smears obtained by scraping from the back card of the inferior turbinate and stained with Wright-Giemsa reveal cylindrical ciliary cylindrical, goblet and basal cells, which are painted in a pale blue color;eosinophils, phylum-Bazo and mast cells are absent, the number of neutrophils and bacteria is negligible;goblet cells content does not exceed 50% of the total number of epithelial cells.

in normal and banal inflammation of eosinophils in the secret of the nasal cavity is not available, or the ratio of eosinophils to it-neutrophil is 1:10.Identification of a large number of eosinophils in the nasal secretions reflects the body's allergic reaction to the introduction of allergens in the upper respiratory tract.Local diagnosis of allergic process is facilitated by the fact that the relative content of eosinophils in tissues and on the surface of the upper respiratory tract mucosa in allergic diseases greatly exceeds their content in the peripheral blood.Especially valuable research

mucus from the nose is for diagnosis of allergic diseases of the nasal cavity and paranasal sinuses.

number of eosinophils in the nasal secretions of allergic processes increases mucosa of the upper respiratory tract, but to different degrees depending on the type of allergen, the allergic-type reactions, remission or exacerbation of allergic disease.Therefore, in some cases, an exacerbation of allergic rhinosinusitis in smears from the nose detect a large number of eosinophils, and in-between period pristupnaya reveal only a few eosinophils;in other cases the difference in the number of eosinophils in the secret depending on the phase of the disease has been observed.The number of eosinophils in the nasal secretions depends on the type of allergen and ways of its penetration into the body.When inhalation allergy a marked eosinophilia and eosinophil count less for food sensitization.Study nasal secretion plays an important role in the differential diagnosis of allergic and vasomotor rhinitis.Eosinophilia is characteristic of allergic rhinitis.The presence of eosinophils in the nasal secretions - an important diagnostic sign not only of allergic rhinitis, and respiratory allergies in general.

In recent years, great importance in the diagnosis of allergic diseases lend detection secret nasal cavity of mast cells.During exacerbation of allergic rhinitis nasal secretions are a large number of eosinophils and mast cells, that is, these cells increase in number runs parallel to, and in the remission maintenance, and decreases the other, but always in eosinophils greater than mast cells.When nasal secretions study paying attention to the number of goblet cells, when it exceeds 50% of all epithelial cells - it also indicates local allergies.Evaluation activity

allergic reaction to the study by scraping with the nasal mucosa (the average number of cells in 10 fields of view at 1,000-fold magnification) is shown in Table Table ..

Evaluation of activity of an allergic reaction to the study by scraping with the nasal mucosa[Lawlor Jr G. et al., 2000]

Table Assessment of the activity of an allergic reaction, according to a study scrapings from the nasal mucosa [Lawlor Jr G. et al., 2000]

relationship between the nature of pathological changes in the scrapings fromnasal mucosa and a presumptive diagnosis is shown in Table ..

Table Changes in scrapings from the nasal mucosa and a presumptive diagnosis

Table Changes in scrapings from the nasal mucosa and a presumptive diagnosis

Likewise examine and evaluate the results of scrapings from the conjunctiva in allergicdiseases of the eye.Increasing the number of eosinophils, basophils and mast cells favors allergic conjunctivitis;the predominance of neutrophils - a bacterial conjunctivitis, conjunctivitis caused by irritants (in conjunction with an increase in the percentage of eosinophils - for allergic conjunctivitis);lymphocytes - about viral conjunctivitis.