Diseases of the respiratory system
Hereditary diseases of the respiratory system
Hereditary respiratory diseases constitute, according to different authors, from 51 to 35% of the total number of patients with lung diseases.
There are actually hereditary diseases of the lungs and respiratory system lesions that accompany various types of hereditary diseases.Monogenic lung disease can be inherited, as with any hereditary diseases.This inheritance can be carried out in an autosomal dominant and autosomal recessive manner.By monogenic diseases include lung Tracheabronchomegalia (Mounier-Kuhn syndrome), Williams-Campbell syndrome, primary ciliary dyskinesia (Kartagener syndrome), primary pulmonary hypertension, hereditary spontaneous pneumothorax, diffuse idiopathic pulmonary fibrosis, isolated pulmonary hemosiderosis, Goodpasture's syndrome, alveolar microlithiasis.Among the hereditary diseases in which pulmonary lesions are one of the main clinical manifestations, should be called cystic fibrosis, as well as various options for primary im
Lung may also arise for other hereditary disorders (Marfan's syndrome, Ehlers-Danlos Syndrome Rowley Rezenberga Syndrome Rendu-Osler-Weber, hemophilia syndrome Klinefelter), which are inherited in an autosomal dominant, autosomal recessive manner, orThey are the result of chromosomal aberrations.However, the most frequently encountered in the pulmonology clinic patients with multifactorial diseases.Among these diseases are bronchial asthma, the prevalence of which in the world is constantly growing, as well as extrinsic allergic alveolitis.Smoking, respiratory infection, and many other factors lead to the formation of emphysema (increase in lightness) of the lungs.
vast majority of hereditary diseases manifest themselves in childhood, are no exception, and lung disease.
severity of congenital and hereditary diseases of the lungs, their recurrent (periodic worsening of the disease) and chronic, decreased performance and disability for both adults and children make the problem not only medical, but also social.However, pessimism about the effectiveness of therapeutic effects in hereditary diseases is not justified.Combined therapy in many patients leads to stabilization of the disease process and improve their condition.