Furosemidzavisimaya kidney - Causes , Symptoms and Treatment .MF .
Currently conditions with the accumulation in the body of excess fluid, are not uncommon.It is conditions such as renal failure with edema, congestive heart failure, liver disease associated with impaired protein synthesis, as well as hypertension.These conditions require the use of diuretics, in particular furosemide, for a long time and often in high doses.
should also mention the attempts to lose weight with the help of furosemide is now particularly common in young women.Such a "diet" is typically characterized reckless use of the drug each day, sometimes in extremely large numbers.
For such conditions, when there is prolonged exposure to furosemide in the body by a doctor's appointment or in the process of self-medication, introduced the term "furosemidzavisimaya kidney."
Symptoms furosemidzavisimoy kidney
for furosemide characterized by dose-dependent effect.That is, increasing the amount of urine is achieved by using different amounts of the drug, due to the underlying disease and the indivi
Furosemide belongs to loop diuretics (diuretics).In the kidney (ascending loop of Henle Division) it inhibits the reuptake of chlorine ions and, as a consequence, the potassium, sodium and hydrogen ions, which increases the amount of urine.In addition, the drug also increases the excretion of calcium and magnesium ions.
Long-term use of furosemide can cause pseudo-Bartterovsky syndrome.It is a pathological condition characterized by severe water and electrolyte disturbances such as hypokalemia (decreased potassium in the blood concentration), hyponatremia (decrease in the concentration of sodium in the blood), chloropenia (reduction of chlorine concentration in the blood), alkalosis (disturbance of acid-base balance, associated with an excess ofbases), signs of dehydration, increased plasma renin activity.
hypokalemia refers to dangerous conditions.In particular, it can provoke a life-threatening arrhythmia, especially in patients at high risk, for example, myocardial infarction, receiving cardiac glycosides, as well as suffering from arrhythmias in the past.potassium losses are increased when using certain drugs.They include glucocorticoids, licorice preparations carbenoxolone, as well as some aromatic means a confectionery composition.
Symptoms of hypokalemia include muscle weakness, pain in the muscles, the feeling of pins and needles, sometimes convulsions.At the same time may cause heart palpitations, disruption of the heart.Blood pressure tends to decrease.It is also a manifestation of hypokalemia are constipation.
Potassium is an essential component for the synthesis of insulin.In patients with diabetes, insulin deficiency can lead to increased blood glucose levels, which may require a revision of medical tactics.
Magnesium deficiency causes an increase in neuromuscular excitability, and as a result, you may experience seizures and the development of cardiac arrhythmias, including atrial fibrillation.
Hyponatremia explains headache, mental changes - excitation or vice versa depressed mood, muscle cramps, weakness and fatigue, nausea and vomiting, not bringing relief.These symptoms are usually associated with the development of edema of nervous system cells.
Chronic fluid loss is manifested by weakness, loss of strength, abnormally low blood pressure, dizziness, drowsiness.
the treatment of furosemide may be a delay in the body of uric acid and gout development .
the treatment of furosemide is enhanced excretion of sodium, potassium and chlorine from the body, which leads to the formation of metabolic alkalosis .Manifestation of alkalosis are muscle cramps, low blood pressure, severe weakness, constipation development.
In addition, a loop diuretic furosemide enhances ototoxicity (negative impact on the hearing) and nephrotoxicity of aminoglycosides (loss of kidney tissue), some cephalosporins.
is also necessary to mention the direct toxic effect of furosemide on renal cells.We describe the cases of glomerulonephritis in patients for a long time to apply furosemide.
Thus, furosemide is a dangerous drug that causes a number of disorders in the body.It should therefore be used only under medical supervision at a constant evaluation of its effectiveness, and, if necessary, with dose adjustments.
the treatment of furosemide determination of blood electrolytes (sodium, potassium, chlorine, magnesium) must be held within 3 months of starting treatment, and then the analysis is appointed every six months.
Treatment furosemidzavisimoy kidney
For prevention of hypokalemia is recommended to increase the content in the diet of foods rich in potassium (dried apricots, nuts, raisins, peas and beans, potatoes, especially baked in their skins, seaweed).Also shown is the use of drugs with potassium, such as asparkam.
Magnesium deficiency is corrected using gluconate and magnesium chloride.In the treatment of hyponatremia sodium chloride necessary to be extremely careful, because salt causes water retention in the body.
When canceling furosemide edema may worsen.It can be as a consequence of the disease, the treatment of which you have registered and furosemide, and depending on the manifestation of furosemide (usually when a diuretic used to lose weight).In the first case, can not do without a doctor's advice and correct treatment for your condition.In the second, you can try to "get off the furosemide", limiting fluid intake while taking minerals potassium and magnesium products.As diuretics at this time to use the gathering of medicinal herbs.Any liquid taken within 3-4 hours of the day.Last meal - not later than 6 pm.The process of getting rid of the dependence of long and takes at least a month, have patience.
WADA Furosemide is banned for use in athletes.He himself is not doping, but as a drug that can lead to the removal of traces of other illicit drugs by increasing the amount of urine and as a means of rapid weight loss, in the sports world is unacceptable.
physician therapist, nephrologist Sirotkin EV